Alglucosidase alfa

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages of lysosomal glycogen. Structurally, Alglucosidase alfa is a glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates. It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.

Price Not Available 1 mg Alglucosidase alfa Supplier Page
Trivial name Alglucosidase alfa
Catalog Number TP-017CL
Alternative Name(s) Alglucosidase alfa
Research Area Metabolic enzyme deficiencies
Molecular Formula C4435H6739N1175O1279S32
CAS# 420784-05-0
Purity >90%
Size 1 mg
Supplier Page https://www.creativebiolabs.net/Alglucosidase-alfa-22355.htm
Additional Information For the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.