C646
Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines.
| Catalog Number | AG-CR1-3508-M001 |
| Alternative Name(s) | (E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid |
| Research Area | Biochemicals, Cancer, Immunology, Stem Cell Research |
| Molecular Formula | C24H19N3O6 |
| CAS# | 328968-36-1 |
| Purity | >98% |
| Inchi | InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12+ |
| Inchi Key | HEKJYZZSCQBJGB-XDHOZWIPSA-N |
| SMILES | CC1=NN(C(=O)C1=CC1=CC=C(O1)C1=CC(C)=C(C)C=C1[N+]([O-])=O)C1=CC=C(C=C1)C(O)=O |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3508/c646.html |