(R,R)-Hymeglusin
beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor.
| Catalog Number | AG-CN2-0103-MM25 |
| Alternative Name(s) | 1233A; F-244; L-659-699 |
| Research Area | Antibiotic, Metabolism, Natural Products, Obesity |
| Molecular Formula | C18H28O5 |
| CAS# | 29066-42-0 |
| Purity | >95% |
| Inchi | InChI=1S/C18H28O5/c1-12(8-13(2)9-14(3)10-17(20)21)6-4-5-7-16-15(11-19)18(22)23-16/h9-10,12,15-16,19H,4-8,11H2,1-3H3,(H,20,21)/b13-9+,14-10+/t12-,15-,16-/m1/s1 |
| Inchi Key | ODCZJZWSXPVLAW-KXCGKLMDSA-N |
| SMILES | C[C@H](CCCC[C@H]1OC(=O)[C@@H]1CO)CC(C)=CC(C)=CC(O)=O |
| Size | 2.5 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0103/-r-r-hymeglusin.html |