IBMX
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.
Catalog Number | AG-CR1-3512-M500 |
Alternative Name(s) | 3-Isobutyl 1-methylxanthine; NSC 165960; EINECS 249-259-3 |
Research Area | Apoptosis, Biochemicals, Cancer, Cell Death, Inflammation |
Molecular Formula | C10H14N4O2 |
CAS# | 28822-58-4 |
Purity | >99% |
Inchi | InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) |
Inchi Key | APIXJSLKIYYUKG-UHFFFAOYSA-N |
SMILES | CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O |
Size | 500 mg |
Supplier Page | http://www.adipogen.com/ag-cr1-3512/ibmx.html |