Thiocolchicine

Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Inhibitor of autophagosome-lysosome fusion. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.

Price Not Available 5 mg Thiocolchicine Supplier Page
Catalog Number AG-CN2-0074-M005
Alternative Name(s) 10-Demethoxy-10-methylthiocolchicine; NSC 186301
Research Area Apoptosis, Autophagy, Cancer, Cell Death, Inflammation, Natural Products
Molecular Formula C22H25NO5S
CAS# 2730-71-4
Purity >95%
Inchi InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
Inchi Key CMEGANPVAXDBPL-UHFFFAOYSA-N
SMILES COC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(SC)=CC=C23)=C1
Size 5 mg
Supplier Page http://www.adipogen.com/ag-cn2-0074/thiocolchicine.html