Thiocolchicine
Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Inhibitor of autophagosome-lysosome fusion. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.
| Catalog Number | AG-CN2-0074-M025 |
| Alternative Name(s) | 10-Demethoxy-10-methylthiocolchicine; NSC 186301 |
| Research Area | Apoptosis, Autophagy, Cancer, Cell Death, Inflammation, Natural Products |
| Molecular Formula | C22H25NO5S |
| CAS# | 2730-71-4 |
| Purity | >95% |
| Inchi | InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24) |
| Inchi Key | CMEGANPVAXDBPL-UHFFFAOYSA-N |
| SMILES | COC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(SC)=CC=C23)=C1 |
| Size | 25 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0074/thiocolchicine.html |