Alsterpaullone
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor.
| Catalog Number | AG-CR1-0036-M001 |
| Alternative Name(s) | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one |
| Research Area | Apoptosis, Biochemicals, Cancer, Cell Death |
| Molecular Formula | C16H11N3O3 |
| CAS# | 237430-03-4 |
| Purity | >98% |
| Inchi | InChI=1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20) |
| Inchi Key | OLUKILHGKRVDCT-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)C1=CC2=C(NC3=C2CC(=O)NC2=C3C=CC=C2)C=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0036/alsterpaullone.html |