Incensol

Component of the frankincense essential oil. Activator of transient receptor potential vanilloid 3 (TRPV3), a heat-sensitive ion channel involved in skin heat sensitivity, thermoregulation and neurological activities. More powerful TRPV3 agonist than incensol acetate (Prod. No. AG-CN2-0484). Potent inhibitor of STAT3. Showed inhibitory activity on IL-6-induced STAT3 activation. Shown to have COX-1 and COX-2 inhibitory activity and cytotoxic activity against selected cancer cell lines.

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Catalog Number	AG-CN2-0482-M001
Alternative Name(s)	(-)-Incensol; (-)-Incensole; (1R,2S,5E,9E,12S)-1,5,9-Trimethyl-12-propan-2-yl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol
Research Area	Biochemicals, Inflammation, Neurobiology
Molecular Formula	C20H34O2
CAS#	22419-74-5
Purity	>92%
Inchi	InChI=1S/C20H34O2/c1-15(2)20-12-11-17(4)8-6-7-16(3)9-10-18(21)19(5,22-20)13-14-20/h7,11,15,18,21H,6,8-10,12-14H2,1-5H3/b16-7+,17-11+/t18-,19+,20+/m0/s1
Inchi Key	SSBZLMMXFQMHDP-REDNKFHQSA-N
SMILES	C/C1=CCC/C(C)=C/C[C@]2(C(C)C)CC[C@@](C)(O2)[C@@H](O)CC1
Size	1 mg
Supplier Page	http://www.adipogen.com/ag-cn2-0482/incensol.html