(S)-(+)-Naproxene

Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II).

Price Not Available 10 g (S)-(+)-Naproxene Supplier Page
Catalog Number CDX-N0061-G010
Alternative Name(s) Naprosyn; Equiproxen; Laraflex; (S)-(+)-6-Methoxy-alpha-methyl-2-naphthalene acetic acid
Research Area Biochemicals, Immunology
Molecular Formula C14H14O3
CAS# 22204-53-1
Purity >98%
Inchi InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)
Inchi Key CMWTZPSULFXXJA-UHFFFAOYSA-N
SMILES COC1=CC=C2C=C(C=CC2=C1)[C@H](C)C(O)=O
Size 10 g
Supplier Page http://www.adipogen.com/cdx-n0061/-s-naproxene.html