Ganglioside GM2 . sodium salt (bovine brain)

Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM2 is a very minor component of the nervous system, but it is accumulated in brains from Tay-Sachs and Sandhoff disease patients, due to genetic defect of lysosomal beta-hexosaminidase.

Price Not Available 500 µg Ganglioside GM2 . sodium salt (bovine brain) Supplier Page

Catalog Number	AG-CN2-9001-C500
Alternative Name(s)	GM2 . Na; Monosialoganglioside GM2 . Na
Research Area	Cancer, Inflammation, Natural Products, Neurobiology, Neurodegenerative Disease
Molecular Formula	C67H120N3O26 . Na
CAS#	19600-01-2
Purity	>98%
Inchi	InChI=1S/C67H121N3O26.Na/c1-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-50(80)70-43(44(77)33-31-29-27-25-23-21-18-16-14-12-10-8-6-2)40-89-64-57(85)56(84)59(48(38-73)91-64)93-65-58(86)62(60(49(39-74)92-65)94-63-52(69-42(4)76)55(83)54(82)47(37-72)90-63)96-67(66(87)88)35-45(78)51(68-41(3)75)61(95-67)53(81)46(79)36-71;/h31,33,43-49,51-65,71-74,77-79,81-86H,5-30,32,34-40H2,1-4H3,(H,68,75)(H,69,76)(H,70,80)(H,87,88);/q;+1/p-1/b33-31+;/t43-,44+,45?,46+,47?,48?,49?,51+,52?,53-,54-,55?,56?,57?,58?,59+,60-,61?,62?,63+,64+,65-,67-;/m0./s1
Inchi Key	YZCIBJIDUSQSAE-AGTWZOCMSA-M
SMILES	[Na+].[H][C@@](O)(CO)[C@]([H])(O)C1O[C@@](CC(O)[C@H]1NC(C)=O)(O[C@@H]1C(O)[C@H](O[C@H]2C(O)C(O)[C@H](OC[C@]([H])(NC(=O)CCCCCCCCCCCCCCCCC)[C@]([H])(O)C=CCCCCCCCCCCCCC)O[C@H]2CO)OC(CO)[C@@H]1O[C@H]1O[C@@H](CO)[C@H](O)C(O)C1NC(C)=O)C([O-])=O
Size	500 µg
Supplier Page	http://www.adipogen.com/ag-cn2-9001/ganglioside-gm2.html