Actinomycin X2
Aniso-Actinomycin (4-Oxopro instead of Pro in the beta-chain). Antitumor and antiviral antibiotic. Antituberculosis agent. Has higher cytotoxicity towards cultured human leukemia (HL-60) cells than actinomycin D. Apoptosis inducer. Forms a complex with DNA and blocks its biological activity.
| Catalog Number | BVT-0375-M005 |
| Alternative Name(s) | Actinomycin A5; Actinomycin B2; Actinomycin V; Actinomycin D, 3A-(4-oxo-L-proline); NSC175006 |
| Research Area | Antibiotic, Apoptosis, Cancer, Immunology, Natural Products |
| Molecular Formula | C62H84N12O17 |
| CAS# | 18865-48-0 |
| Purity | >98% |
| Inchi | InChI=1S/C62H84N12O17/c1-26(2)41-58(84)73-22-17-18-35(73)57(83)69(13)24-37(76)71(15)47(28(5)6)61(87)89-32(11)43(55(81)65-41)67-53(79)34-20-19-30(9)51-45(34)64-46-39(40(63)50(78)31(10)52(46)91-51)54(80)68-44-33(12)90-62(88)48(29(7)8)72(16)38(77)25-70(14)60(86)49-36(75)21-23-74(49)59(85)42(27(3)4)66-56(44)82/h19-20,26-29,32-33,35,41-44,47-49H,17-18,21-25,63H2,1-16H3,(H,65,81)(H,66,82)(H,67,79)(H,68,80)/t32-,33-,35-,41-,42-,43-,44-,47-,48-,49+/m1/s1 |
| Inchi Key | SMBASHZPOHFQRU-ILYIJYFNSA-N |
| SMILES | [H][C@]12CCCN1C(=O)[C@H](NC(=O)[C@H](NC(=O)C1=C3N=C4C(OC3=C(C)C=C1)=C(C)C(=O)C(N)=C4C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@]3([H])N(CCC3=O)C(=O)[C@H](NC1=O)C(C)C)[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/bvt-0375/actinomycin-x2.html |