Z-Leu-Leu-Leu-B(OH)2 [MG-262]

Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Similar structure as MG-132 (AG-CP3-0011) but much higher potency.

Catalog Number AG-CP3-0024-M001
Alternative Name(s) Z-LLL-B(OH)2; Proteasome Inhibitor III
Research Area Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death, Immunology, Neurobiology
Molecular Formula C25H42BN3O6
CAS# 179324-22-2
Purity >95%
Inchi InChI=1S/C25H42BN3O6/c1-16(2)12-20(24(31)29-22(26(33)34)14-18(5)6)27-23(30)21(13-17(3)4)28-25(32)35-15-19-10-8-7-9-11-19/h7-11,16-18,20-22,33-34H,12-15H2,1-6H3,(H,27,30)(H,28,32)(H,29,31)/t20-,21-,22-/m0/s1
Inchi Key MWKOOGAFELWOCD-FKBYEOEOSA-N
SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)B(O)O
Size 1 mg
Supplier Page http://www.adipogen.com/ag-cp3-0024/z-leu-leu-leu-b-oh-2-mg-262.html