Andrastin A
Mycotoxin. Protein farnesyltransferase (PFTase) inhibitor. Anti-cancer compound. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells.
Catalog Number | AG-CN2-0144-C250 |
Research Area | Cancer, Natural Products |
Molecular Formula | C28H38O7 |
CAS# | 174232-42-9 |
Purity | >95% |
Inchi | InChI=1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,18-20,32H,9-12H2,1-8H3/t18-,19-,20+,25+,26+,27+,28-/m1/s1 |
Inchi Key | SNSSSENJBPCLPM-OXILWVMOSA-N |
SMILES | [H]C(=O)[C@@]12CC[C@H](OC(C)=O)C(C)(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])C=C(C)[C@@]2(C)C(=O)C(C)=C(O)[C@@]12C(=O)OC |
Size | 250 µg |
Supplier Page | http://www.adipogen.com/ag-cn2-0144/andrastin-a.html |