FTY720 . hydrochloride
Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when phosphorylated by sphingosine kinase. Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 activity enhancer. Cytosolic phospholipase A2 inhibitor, independent of sphingosine 1-phosphate receptors. Autophagy inducer. Apoptosis inducer.
| Catalog Number | AG-CR1-3587-M001 |
| Alternative Name(s) | 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol . HCl; Fingolimod; Gilenya |
| Research Area | Apoptosis, Autophagy, Biochemicals, Cancer, Immunology, Inflammation |
| Molecular Formula | C19H33NO2 . HCl |
| CAS# | 162359-56-0 |
| Purity | >98% |
| Inchi | InChI=1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H |
| Inchi Key | SWZTYAVBMYWFGS-UHFFFAOYSA-N |
| SMILES | [Cl-].CCCCCCCCC1=CC=C(CCC([NH3+])(CO)CO)C=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3587/fty720-hydrochloride.html |