LY-294,002
Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.
| Catalog Number | AG-CR1-0108-M005 |
| Alternative Name(s) | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Research Area | Autophagy, Biochemicals, Cancer |
| Molecular Formula | C19H17NO3 |
| CAS# | 154447-36-6 |
| Purity | >99% |
| Inchi | InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 |
| Inchi Key | CZQHHVNHHHRRDU-UHFFFAOYSA-N |
| SMILES | O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCOCC1 |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0108/ly-294-002.html |