SB202190
Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Autophagic vacuole inducer
Catalog Number | AG-CR1-0028-M001 |
Alternative Name(s) | FHPI; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole |
Research Area | Apoptosis, Biochemicals, Cancer, Cell Death |
Molecular Formula | C20H14FN3O |
CAS# | 152121-30-7 |
Purity | >97% |
Inchi | InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24) |
Inchi Key | QHKYPYXTTXKZST-UHFFFAOYSA-N |
SMILES | OC1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1 |
Size | 1 mg |
Supplier Page | http://www.adipogen.com/ag-cr1-0028/sb202190.html |