Bisindolylmaleimide XI . hydrochloride [Ro 32-0432]
Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo.
| Catalog Number | AG-CR1-0109-M001 |
| Alternative Name(s) | Ro 32-0432; BIM XI |
| Research Area | Biochemicals, Cancer, Inflammation |
| Molecular Formula | C28H28N4O2 . HCl |
| CAS# | 145333-02-4 |
| Purity | >98% |
| Inchi | InChI=1S/C28H28N4O2.ClH/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21;/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34);1H |
| Inchi Key | HSPRASOZRZDELU-UHFFFAOYSA-N |
| SMILES | Cl.CN(C)CC1CCN2C(C1)=C(C1=C2C=CC=C1)C1=C(C(=O)NC1=O)C1=CN(C)C2=C1C=CC=C2 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0109/bisindolylmaleimide-xi-hydrochloride.html |