Bisindolylmaleimide X . hydrochloride [Ro 31-8425]
Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils.
| Catalog Number | AG-CR1-0113-M005 |
| Alternative Name(s) | Ro 31-8425; BIM X |
| Research Area | Biochemicals, Cancer, Inflammation |
| Molecular Formula | C26H24N4O2 . HCl |
| CAS# | 145317-11-9 | 131848-97-0 (free base) |
| Purity | >98% |
| Inchi | InChI=1S/C26H24N4O2.ClH/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30;/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32);1H |
| Inchi Key | IMBOYWXMTUUYGZ-UHFFFAOYSA-N |
| SMILES | CC(C)(C=C)C12CC3N(C1NC1=C2C=CC=C1)C(=O)C1CC2(C(NC4=C2C=CC=C4)N1C3=O)C(C)(C)C=C |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0113/bisindolylmaleimide-x-hydrochloride.html |