Z-VRPR-FMK

Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-kappaB-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma (GCB-DLBCL) cell lines. Shown to inhibit the autoprocessing activity of MCA2ac (calcium dependent) in Trypanosoma brucei.

Price Not Available 1 mg Z-VRPR-FMK Supplier Page
Catalog Number AG-CP3-0008-M001
Alternative Name(s) Z-Val-Arg-Pro-DL-Arg-FMK . TFA
Research Area Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death, Inflammasomes, Inflammation, Necrosis, Neurodegenerative Disease
Molecular Formula C31H49FN10O6 . C2HF3O2
CAS# 1381885-28-4 (free base)
Purity >90%
Inchi InChI=1S/C31H49FN10O6/c1-19(2)25(41-31(47)48-18-20-9-4-3-5-10-20)27(45)40-22(12-7-15-38-30(35)36)28(46)42-16-8-13-23(42)26(44)39-21(24(43)17-32)11-6-14-37-29(33)34/h3-5,9-10,19,21-23,25H,6-8,11-18H2,1-2H3,(H,39,44)(H,40,45)(H,41,47)(H4,33,34,37)(H4,35,36,38)/t21?,22-,23-,25-/m0/s1
Inchi Key DYQKGOBRZWMAHV-YTJMMMLMSA-N
SMILES OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
Size 1 mg
Supplier Page http://www.adipogen.com/ag-cp3-0008/z-vrpr-fmk.html