beta-Mannosylceramide
Potent stimulator of invariant natural killer T (iNKT) cells. Induces strong antitumor immunity through a nitric oxide (NO) and TNF-alpha dependent mechansim, different compared to the IFN-gamma dependent mechanism of alpha-GalCer (AG-CN2-0014). Does not induce anergy of iNKT cells.
| Catalog Number | AG-CR1-3621-M001 |
| Alternative Name(s) | beta-ManCer; beta-Mannosyl Ceramide; (2S,3S,4R)-2-Amino-N-hexacosanoyl-1-O-(beta-D-mannopyranosyl)-1,3,4-octadecanetriol |
| Research Area | Biochemicals, Cancer, Immunology, Inflammation, Natural Products, Neurobiology, Neurodegenerative Disease |
| Molecular Formula | C50H99NO9 |
| CAS# | 1334332-65-8 |
| Purity | >95% |
| Inchi | InChI=1S/C50H99NO9/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-26-27-29-31-33-35-37-39-45(54)51-42(41-59-50-49(58)48(57)47(56)44(40-52)60-50)46(55)43(53)38-36-34-32-30-28-16-14-12-10-8-6-4-2/h42-44,46-50,52-53,55-58H,3-41H2,1-2H3,(H,51,54)/t42-,43+,44+,46-,47+,48-,49-,50+/m0/s1 |
| Inchi Key | VQFKFAKEUMHBLV-JDMIZZMOSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](COC1OC(CO)C(O)C(O)C1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3621/beta-mannosylceramide.html |