Z-Leu-Leu-Nva-CHO [MG-115]
Potent, reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Apoptosis inducer in Rat-1 and PC12 cells via a p53-dependent pathway. Autophagy activator.
Catalog Number | AG-CP3-0015-M005 |
Alternative Name(s) | Z-LLNva-CHO; Proteasome Inhibitor |
Research Area | Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death, Immunology, Neurobiology |
Molecular Formula | C25H39N3O5 |
CAS# | 133407-86-0 |
Purity | >95% |
Inchi | InChI=1S/C25H39N3O5/c1-6-10-20(15-29)26-23(30)21(13-17(2)3)27-24(31)22(14-18(4)5)28-25(32)33-16-19-11-8-7-9-12-19/h7-9,11-12,15,17-18,20-22H,6,10,13-14,16H2,1-5H3,(H,26,30)(H,27,31)(H,28,32)/t20-,21-,22-/m0/s1 |
Inchi Key | QEJRGURBLQWEOU-FKBYEOEOSA-N |
SMILES | [H]C(=O)[C@H](CCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1 |
Size | 5 mg |
Supplier Page | http://www.adipogen.com/ag-cp3-0015/z-leu-leu-nva-cho-mg-115.html |