MPLA (synthetic) Sterile Solution

Toll-like receptor 4 (TLR4) activator. Activates TLR4 but does not activate TLR2 even at high concentrations. Defined structure of MPLA. Synthetic lipid A is structurally very similar to natural MPLA but does not exist in nature.

Catalog Number AG-CU1-0002-C100
Alternative Name(s) Monophosphoryl Lipid A; Phosphorylated Hexaacyl Disaccharide; Glycopyranoside Lipid A; Glucopyranosyl Lipid Adjuvant; GLA
Research Area Autophagy, Biochemicals, Immunology, Inflammation, Natural Products
Molecular Formula C96H184N3O22P
CAS# 1246298-63-4
Inchi InChI=1/C96H181N2O22P.H3N/c1-7-13-19-25-31-37-39-45-51-57-63-69-85(104)114-79(67-61-55-49-43-35-29-23-17-11-5)73-84(103)98-90-94(119-88(107)74-80(68-62-56-50-44-36-30-24-18-12-6)115-86(105)70-64-58-52-46-40-38-32-26-20-14-8-2)92(120-121(110,111)112)81(75-99)117-96(90)113-76-82-91(108)93(118-87(106)72-78(101)66-60-54-48-42-34-28-22-16-10-4)89(95(109)116-82)97-83(102)71-77(100)65-59-53-47-41-33-27-21-15-9-3;/h77-82,89-96,99-101,108-109H,7-76H2,1-6H3,(H,97,102)(H,98,103)(H2,110,111,112);1H3/t77-,78-,79-,80-,81?,82?,89?,90?,91-,92-,93?,94?,95+,96-;/m1./s1/fC96H180N2O22P.H4N/h97-98,110H;1H/q-1;+1
Inchi Key UPAZUDUZKTYFBG-UCUVALOBDI
SMILES [NH4+].CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@H](OCC2O[C@H](O)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)C(OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)OC(CO)[C@@H](OP(O)([O-])=O)C1OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
Size 100 µg
Supplier Page http://www.adipogen.com/ag-cu1-0002/mpla-synthetic-tlrpure-sterile-solution.html