Tripolin A
Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.
| Catalog Number | AG-CR1-3520-M001 |
| Alternative Name(s) | (3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one |
| Research Area | Biochemicals, Cancer |
| Molecular Formula | C15H11NO3 |
| CAS# | 1148118-92-6 |
| Purity | >98% |
| Inchi | InChI=1S/C15H11NO3/c17-10-5-6-14(18)9(7-10)8-12-11-3-1-2-4-13(11)16-15(12)19/h1-8,17-18H,(H,16,19)/b12-8- |
| Inchi Key | OMKSBDLWMROKNU-WQLSENKSSA-N |
| SMILES | OC1=CC=C(O)C(C=C2/C(=O)NC3=C2C=CC=C3)=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3520/tripolin-a.html |