EM574 [Motilide]
Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor).
| Catalog Number | AG-CN2-0102-C250 |
| Alternative Name(s) | Motilide; Idremcinal; 8,9-Didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin |
| Research Area | Biochemicals, Metabolism, Neurobiology |
| Molecular Formula | C39H69NO12 |
| CAS# | 110480-13-2 |
| Purity | >95% |
| Inchi | InChI=1S/C39H69NO12/c1-15-27-39(12,45)32(42)22(6)30-20(4)17-38(11,52-30)34(51-36-29(41)26(16-21(5)47-36)40(13)19(2)3)23(7)31(24(8)35(44)49-27)50-28-18-37(10,46-14)33(43)25(9)48-28/h19,21-29,31-34,36,41-43,45H,15-18H2,1-14H3/t21-,22+,23+,24-,25+,26+,27-,28+,29-,31+,32-,33+,34-,36+,37?,38-,39-/m1/s1 |
| Inchi Key | FPBKIOZMKHHNLL-FMUXYZBNSA-N |
| SMILES | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |
| Size | 250 µg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0102/em574.html |