Glucopiericidin A

ADCs Toxins, Glucopiericidin A is a natural bioactive compound. Glucopiericidin A (GPA) interestingly alone did not inhibit filopodia protrusion, but synergistically inhibit protrusion with the mitochondrial respiration inhibitor, piericidin A (PA). These results suggested that GPA might inhibit glycolysis. GPA may therefore serve as a glucose transporter chemical probe. Simultaneous inhibition of both glycolysis and mitochondrial respiration dramatically decreased intracellular ATP levels, indicating that GPA inhibits ATP-dependent filopodia protrusion with PA. HCT-116: IC50=1,73 uM; PSN1 : IC50=>8,67 uM; T98G : IC50=>8,67 uM; A549 : IC50=0,87 uM (preliminary laboratory results). Journal of Antibiotics (1989), 42, 1734.

Price Not Available 1 mg Glucopiericidin A Supplier Page
Trivial name Glucopiericidin A
Catalog Number ADC-P-093
Alternative Name(s) Glucopiericidin A
Research Area ADC research
CAS# 108073-65-0
Purity >95%
Size 1 mg
Supplier Page https://www.creative-biolabs.com/adc/classify-adc-toxins-6.htm
Additional Information Not fully tested. For research use only. Not for human use. We do not sell to patients.