GYY 4137
Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism.
| Catalog Number | AG-CR1-3513-M010 |
| Alternative Name(s) | 4-Methoxyphenyl(morpholino)phosphinodithioate morpholinium salt |
| Research Area | Biochemicals, Cancer, Immunology, Inflammation |
| Molecular Formula | C11H16NO2PS2 . C4H9NO |
| CAS# | 106740-09-4 |
| Purity | >95% |
| Inchi | InChI=1S/C11H16NO2PS2.C4H9NO/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2 |
| Inchi Key | YZMHNNLDUWRZFW-UHFFFAOYSA-N |
| SMILES | C1COCC[NH2+]1.COC1=CC=C(C=C1)P([S-])(=S)N1CCOCC1 |
| Size | 10 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3513/gyy-4137.html |