Leupeptin . hemisulfate

Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant and anti-inflammatory agent. Widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.

Price Not Available 100 mg Leupeptin . hemisulfate Supplier Page
Catalog Number AG-CP3-7000-M100
Alternative Name(s) Acetyl-L-leucyl-L-leucyl-L-argininal . hemisulfate
Research Area Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death, Immunology, Metabolism, Neurobiology, Neurodegenerative Disease
Molecular Formula C20H38N6O4 . 0.5 H2SO4
CAS# 103476-89-7
Purity >97%
Inchi 1S/2C20H38N6O4.H2O4S/c2*1-12(2)​9-16(24-14(5)​28)​19(30)​26-17(10-13(3)​4)​18(29)​25-15(11-27)​7-6-8-23-20(21)​22;1-5(2,3)​4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)​(H,25,29)​(H,26,30)​(H4,21,22,23)​;(H2,1,2,3,4)​/t2*15-,16-,17-;/m00./s1
Inchi Key CIPMKIHUGVGQTG-VFFZMTJFSA-N
SMILES OS(O)(=O)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
Size 100 mg
Supplier Page http://www.adipogen.com/ag-cp3-7000/leupeptin.html