Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsitePhosphatase substarte (4-Nitrophenyl phosphate disodium hexahydrate, p-nitrophenyl phosphate disodium hexahydrate) is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. It is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm.
More Information Supplier PagePhosphatidylserine (Distearoylphosphatidylserine) is a negatively charged glycerophospholipid found mainly in the plasma membrane (PM) and in the late secretory/endocytic compartments, where it regulates cellular activity and can mediate apoptosis It also inhibits inflammatory responses.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
More Information Supplier PagePhosphatidylserine (Distearoylphosphatidylserine) is a negatively charged glycerophospholipid found mainly in the plasma membrane (PM) and in the late secretory/endocytic compartments, where it regulates cellular activity and can mediate apoptosis It also inhibits inflammatory responses.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
More Information Supplier PagePhospho(enol)pyruvic acid monopotassium salt (Potassium 1-carboxyvinyl hydrogenphosphate) is an endogenous metabolite.
More Information Supplier PagePhosphocholine (Phosphorylcholine) chloride calcium salt tetrahydrate is an active endogenous metabolite.
More Information Supplier PagePhosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.
More Information Supplier PagePhosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.
More Information Supplier PagePhosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.
More Information Supplier PagePhosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.
More Information Supplier PagePhosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.
More Information Supplier PagePHPS1 (PTP Inhibitor V), a potent and cell-permeable inhibitor, is specific for Shp2 with Ki value of 0.73 μM.
More Information Supplier PagePHPS1 (PTP Inhibitor V), a potent and cell-permeable inhibitor, is specific for Shp2 with Ki value of 0.73 μM.
More Information Supplier PagePhryma Leptostachya L. Var. Asiatica Hara Extract is derived from Phryma leptostachya L. subsp. asiatica (Hara) Kitamura.
More Information Supplier PagePHT-427 (CS-0223) is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains of Akt and PDPK1) with Ki of 2.7 μM and 5.2 μM, respectively.
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Phthalic acid (1,2-Benzenedioic acid) is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.
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Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
More Information Supplier PagePHTPP is an ERβ selective antagonist with 36-fold selective for ER βover ERα.
More Information Supplier PagePHTPP is an ERβ selective antagonist with 36-fold selective for ER βover ERα.
More Information Supplier PagePHY34 is a late-stage autophagy inhibitor with nanomolar potency and significant antitumor efficacy as a single agent against HGSOC in vivo.
More Information Supplier PagePhycocyanobilin (PCB) is an open-chain tetrapyrrole chromophore covalently bonded to both polypeptide chains of C-Phycocyanin (C-PC), the most represented biliprotein of Spirulina platensis, the mechanisms by which it protected cells included the reduction of oxidative stress damage, which could contribute to its clinical efficacy for the treatment of neurodegenerative diseases.This product has poor solubility, animal […]
More Information Supplier PagePhycocyanobilin (PCB) is an open-chain tetrapyrrole chromophore covalently bonded to both polypeptide chains of C-Phycocyanin (C-PC), the most represented biliprotein of Spirulina platensis, the mechanisms by which it protected cells included the reduction of oxidative stress damage, which could contribute to its clinical efficacy for the treatment of neurodegenerative diseases.This product has poor solubility, animal […]
More Information Supplier PagePhycocyanobilin (PCB) is an open-chain tetrapyrrole chromophore covalently bonded to both polypeptide chains of C-Phycocyanin (C-PC), the most represented biliprotein of Spirulina platensis, the mechanisms by which it protected cells included the reduction of oxidative stress damage, which could contribute to its clinical efficacy for the treatment of neurodegenerative diseases.This product has poor solubility, animal […]
More Information Supplier PagePhycocyanobilin (PCB) is an open-chain tetrapyrrole chromophore covalently bonded to both polypeptide chains of C-Phycocyanin (C-PC), the most represented biliprotein of Spirulina platensis, the mechanisms by which it protected cells included the reduction of oxidative stress damage, which could contribute to its clinical efficacy for the treatment of neurodegenerative diseases.This product has poor solubility, animal […]
More Information Supplier PagePhyllanthus Emblica Extract is extracted from Phyllanthus emblica, which has antidiabetic, hypolipidemic, antibacterial, antioxidant, antiulcerogenic, hepatoprotective, gastroprotective, and chemopreventive properties.
More Information Supplier PagePhyllanthus Urinaria Extract is extracted from Phyllanthus urinaria (L.), which is used to treat jaundice, diabetes, malaria, and liver diseases.
More Information Supplier PagePhysalis Alkekengi Extract is extracted from Physalis alkekengi, which has effects on hyperglycemia by inhibition of oxidative stress, inflammation, and apoptosis, making it a good adjuvant option in diabetes.
More Information Supplier PagePhytic acid (Inositol polyphosphate, Inositol hexakisphosphate) is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
More Information Supplier PagePhytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.
More Information Supplier PagePhytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.
More Information Supplier PagePhytohemagglutininPhytohemagglutinin (PHA) is expressed in Pichia pastoris using native signal peptides, or the Saccharomyces alpha-factor preprosequence, to direct proteins into the secretory pathway. Phytohemagglutinin induces apoptosis in human HEp-2 carcinoma cells via increasing proapoptotic protein Bax and activating caspases-3.
More Information Supplier PagePhytohemagglutininPhytohemagglutinin (PHA) is expressed in Pichia pastoris using native signal peptides, or the Saccharomyces alpha-factor preprosequence, to direct proteins into the secretory pathway. Phytohemagglutinin induces apoptosis in human HEp-2 carcinoma cells via increasing proapoptotic protein Bax and activating caspases-3.
More Information Supplier PagePhytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.
More Information Supplier PagePhytolaccae Radix Extract is extracted from Phytolaccae Radix (the dried root of Phytolacca acinosa Roxb. or Phytolacca americana L.). Radix Phytolaccae is widely used for the treatment of inflammation-related diseases.
More Information Supplier PagePhytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae.
More Information Supplier PagePhytosterols, also called plant sterols or stanol esters, are specialized compounds found in plants that are structurally similar to cholesterol found in humans.
More Information Supplier PagePhytosterols, also called plant sterols or stanol esters, are specialized compounds found in plants that are structurally similar to cholesterol found in humans.
More Information Supplier PagePI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
More Information Supplier PagePI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
More Information Supplier PagePI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
More Information Supplier PagePI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
More Information Supplier PagePI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 nM with little effects on the other two major proteasome proteolytic activities, trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
More Information Supplier PagePI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 nM with little effects on the other two major proteasome proteolytic activities, trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
More Information Supplier PagePI-273, the first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM, can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis.
More Information Supplier PagePI-3065 is a selective p110δ inhibitor with IC50 of 15 nM, >70-fold selectivity over other PI3K family members.
More Information Supplier PagePI-3065 is a selective p110δ inhibitor with IC50 of 15 nM, >70-fold selectivity over other PI3K family members.
More Information Supplier PageA unique collection of 348 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
More Information Supplier PageA unique collection of 348 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
More Information Supplier PagePI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with antitumor activity.
More Information Supplier PagePI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with antitumor activity.
More Information Supplier PagePI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ with an IC50 of 3.6 nM. It also exhibits weak inhibition of PI3KC2γ, PI3Kα, and PI4KIIIα, and
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