PI-103
PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
| Trivial name | N/A |
| Catalog Number | S1038 |
| Molecular Formula | C19H16N4O3 |
| CAS# | 371935-74-9 |
| Inchi | InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2 |
| Inchi Key | TUVCWJQQGGETHL-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/PI-103.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PI-103-chemical-structure-S1038.gif |