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Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

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(+)-Fangchinoline 25mg  | Purity Not Available

Selleck Chemicals

Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.

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(+)-Gallocatechin 1mg  | Purity Not Available

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(+)-Gallocatechin, found notably in green tea, has moderate affinity to the human cannabinoid receptor and acts as an antioxidant.

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(+)-Guaiacin 5mg  | Purity Not Available

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(+)-Guaiacin, found in herbs and spices, belongs to the class of organic compounds known as aryltetralin lignans.

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(+)-Isocorynoline 1mg  | Purity Not Available

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Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.

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(+)-JQ1 25mg  | Purity Not Available

Selleck Chemicals

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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(+)-JQ1 100mg  | Purity Not Available

Selleck Chemicals

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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(+)-JQ1 10mM/1mL  | Purity Not Available

Selleck Chemicals

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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(+)-JQ1 1g  | Purity Not Available

Selleck Chemicals

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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(+)-JQ1 10mg  | Purity Not Available

Selleck Chemicals

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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(+)-JQ1 carboxylic acid 5mg  | Purity Not Available

Selleck Chemicals

(+)-JQ1 carboxylic acid ((+)-JQ1-COOH) is a (+)-JQ1 with a carboxylic acid functional group. (+)-JQ1 carboxylic acid ((+)-JQ1-COOH) can be used as a precursor to a PROTAC that targets BET bromodomains after conjugation to a linker and E3 ligase ligand.

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(+)-JQ1 carboxylic acid 25mg  | Purity Not Available

Selleck Chemicals

(+)-JQ1 carboxylic acid ((+)-JQ1-COOH) is a (+)-JQ1 with a carboxylic acid functional group. (+)-JQ1 carboxylic acid ((+)-JQ1-COOH) can be used as a precursor to a PROTAC that targets BET bromodomains after conjugation to a linker and E3 ligase ligand.

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(+)-JQ1 carboxylic acid 10mM/1mL  | Purity Not Available

Selleck Chemicals

(+)-JQ1 carboxylic acid ((+)-JQ1-COOH) is a (+)-JQ1 with a carboxylic acid functional group. (+)-JQ1 carboxylic acid ((+)-JQ1-COOH) can be used as a precursor to a PROTAC that targets BET bromodomains after conjugation to a linker and E3 ligase ligand.

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(+)-Longifolene 25mg  | Purity Not Available

Selleck Chemicals

(+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins

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(+)-Matrine 100mg  | Purity Not Available

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Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.

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(+)-Matrine 500mg  | Purity Not Available

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Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.

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(+)-Praeruptorin A 1mg  | Purity Not Available

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Praeruptorin A is a coumarin compound naturally occurring in the roots of Peucedanum praeruptorum Dunn., a commonly used traditional Chinese medicine for the treatment of certain respiratory diseases and hypertension. Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation. (+)-Praeruptorin A is one of enantiomers.

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(+)-Usniacin 10mg  | Purity Not Available

Selleck Chemicals

(+)-Usniacin (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.

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(+)-Usniacin 50mg  | Purity Not Available

Selleck Chemicals

(+)-Usniacin (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.

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(+)-α-Lipoic acid 1g  | Purity Not Available

Selleck Chemicals

(+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. R(+)-α-lipoic acid is an essential cofactor of mitochondrial enzyme complexes. R(+)-α-lipoic acid inhibits NF-κB-dependent HIV-1 LTR activation.

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(+)-α-Lipoic acid 25mg  | Purity Not Available

Selleck Chemicals

(+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. R(+)-α-lipoic acid is an essential cofactor of mitochondrial enzyme complexes. R(+)-α-lipoic acid inhibits NF-κB-dependent HIV-1 LTR activation.

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(+/-)-Naringenin 5mg  | Purity Not Available

Selleck Chemicals

(±)-Naringenin, a natural flavonoid present in citrus fruits, induces apoptosis and cytotoxicity in cancer cells.

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(+/-)-Naringenin 25mg  | Purity Not Available

Selleck Chemicals

(±)-Naringenin, a natural flavonoid present in citrus fruits, induces apoptosis and cytotoxicity in cancer cells.

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(+/-)-Sulfinpyrazone 100mg  | Purity Not Available

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Sulfinpyrazone (G-28315, NSC 75925) is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules.

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(+/-)-Sulfinpyrazone 500mg  | Purity Not Available

Selleck Chemicals

Sulfinpyrazone (G-28315, NSC 75925) is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules.

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(±)-Equol 5mg  | Purity Not Available

Selleck Chemicals

(±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.

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(±)-Methyl Jasmonate 25mg  | Purity Not Available

Selleck Chemicals

(±)-Methyl Jasmonate (MeJA, Methyl jasmonate, Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate), a phytohormone that acts as a vital cell regulator in plants, is a new candidate for the treatment of Inflammatory bowel diseases (IBDs), modulating the expression of the major classes of caspase-type protease families.

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(±)-Methyl Jasmonate 1g  | Purity Not Available

Selleck Chemicals

(±)-Methyl Jasmonate (MeJA, Methyl jasmonate, Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate), a phytohormone that acts as a vital cell regulator in plants, is a new candidate for the treatment of Inflammatory bowel diseases (IBDs), modulating the expression of the major classes of caspase-type protease families.

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(±)-Naringenin 100mg  | Purity Not Available

Selleck Chemicals

(±)-Naringenin is a naturally occurring flavonoid. (±)-Naringenin displays a vasorelaxant effect on endothelium-denuded vessels via activating BKCa channels in myocytes.

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(±)-Naringenin 1g  | Purity Not Available

Selleck Chemicals

(±)-Naringenin is a naturally occurring flavonoid. (±)-Naringenin displays a vasorelaxant effect on endothelium-denuded vessels via activating BKCa channels in myocytes.

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(±)-α-Bisabolol 25ul  | Purity Not Available

Selleck Chemicals

α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.

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(±)-α-Tocopherol 25mg  | Purity Not Available

Selleck Chemicals

(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.

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(±)-α-Tocopherol 1g  | Purity Not Available

Selleck Chemicals

(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.

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(−)-Norepinephrine 25mg  | Purity Not Available

Selleck Chemicals

(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.

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(−)-Norepinephrine 100mg  | Purity Not Available

Selleck Chemicals

(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.

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(−)-β-Pinene 25ul  | Purity Not Available

Selleck Chemicals

(−)-β-Pinene (Nopinene) is a natural organic compound in various plants. It is lethal to S. littoralis third instar larvae (LD50 = 65 μg/larva), inhibits infectious bronchitis virus (IBV) replication (IC50 = 1.32 mM) and exhibits a cytotoxic concentration (CC50) value of greater than 10 mM in Vero cells.

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(1S)-(-)-α-Pinene 25ul  | Purity Not Available

Selleck Chemicals

α-Pinene is found in the oils of many species of many coniferous trees, notably the pine and has insecticidal activity. (1S)-(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site.

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(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) 1g  | Purity Not Available

Selleck Chemicals

(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin) is a well-known sugar used in drug delivery, genetic vectors, environmental protection, and the treatment of Niemann-Pick disease type C1 (NPC1). It is an inhibitor of amyloid-β aggregation and widely used drug delivery vehicle to improve stability and bioavailability.

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(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) 25mg  | Purity Not Available

Selleck Chemicals

(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin) is a well-known sugar used in drug delivery, genetic vectors, environmental protection, and the treatment of Niemann-Pick disease type C1 (NPC1). It is an inhibitor of amyloid-β aggregation and widely used drug delivery vehicle to improve stability and bioavailability.

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(20R)-Ginsenoside Rh1 1mg  | Purity Not Available

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(20R)-Ginsenoside Rh1, isolated from the root of Panax Ginseng, exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer.

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(20R)Ginsenoside Rg3 1mg  | Purity Not Available

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(20R)Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It has a role as an antioxidant and a plant metabolite.

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(20R)Ginsenoside Rh2 1mg  | Purity Not Available

Selleck Chemicals

(20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor.,

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(20S)-Protopanaxadiol 10mg  | Purity Not Available

Selleck Chemicals

20(S)-Protopanaxadiol (PPD, 20-Epiprotopanaxadiol), the main intestinal metabolite of ginsenosides, is one of the active ingredients in ginseng. 20(S)-Protopanaxadiol inhibits P-glycoprotein in multidrug resistant cancer cells.

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(20S)-Protopanaxadiol 50mg  | Purity Not Available

Selleck Chemicals

20(S)-Protopanaxadiol (PPD, 20-Epiprotopanaxadiol), the main intestinal metabolite of ginsenosides, is one of the active ingredients in ginseng. 20(S)-Protopanaxadiol inhibits P-glycoprotein in multidrug resistant cancer cells.

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(20S)-Protopanaxatriol 5mg  | Purity Not Available

Selleck Chemicals

(20S)-Protopanaxatriol (g-PPT, 20(S)-APPT), a neuroprotective metabolite of ginsenoside, protopanaxatriol (g-PPT), is a functional ligand for both GR and ERbeta and could modulate endothelial cell functions through the glucocorticoid receptor (GR) and estrogen receptor (ER).

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