MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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JNJ-49095397 | MedChemExpress (MCE) 5 mg  | 99.85%

MedChem Express

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma[1].

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JNJ-49095397 | MedChemExpress (MCE) 10 mg  | 99.85%

MedChem Express

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma[1].

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JNJ-49095397 | MedChemExpress (MCE) 25 mg  | 99.85%

MedChem Express

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma[1].

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JNJ-49095397 | MedChemExpress (MCE) 50 mg  | 99.85%

MedChem Express

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma[1].

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JNJ-49095397 | MedChemExpress (MCE) 100 mg  | 99.85%

MedChem Express

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma[1].

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JNJ-56022486 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNJ-56022486 is an orally active and potent negative AMPA receptor modulator (Ki=19 nM) selective for?TARP-γ8. JNJ-56022486 is also a TARP-γ8 receptor antagonist, with blood?brain?barrier (BBB) permeability. JNJ-56022486 can be used for research of Epilepsy[1][2].

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JNJ-61803534 | MedChemExpress (MCE) 25 mg  | 99.88%

MedChem Express

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6  nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions[1].

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JNJ-61803534 | MedChemExpress (MCE) 50 mg  | 99.88%

MedChem Express

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6  nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions[1].

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JNJ-61803534 | MedChemExpress (MCE) 10 mM * 1 mL  | 99.88%

MedChem Express

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6  nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions[1].

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JNJ-61803534 | MedChemExpress (MCE) 5 mg  | 99.88%

MedChem Express

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6  nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions[1].

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JNJ-61803534 | MedChemExpress (MCE) 10 mg  | 99.88%

MedChem Express

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6  nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions[1].

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JNJ-64264681 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNJ-64264681 is a potent, orally active, selective and irreversible covalent BTK inhibitor. JNJ-64264681 exhibits good pharmacokinetic characteristics and can be used for cancer and autoimmune diseases research[1].

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JNK Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

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JNK Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

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JNK Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

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JNK-1-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor (IC50: 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC50s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun. JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis[1].

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JNK-IN-12 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor (IC50=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125 (HY-12041). JNK-IN-12 doesn’t inhibit nuclear JNK signaling, but does inhibit mitochondrial JNK phosphorylation. JNK-IN-12 helps to improve the Parkinson’s disease (PD) both in vitro and in vivo[1].

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JNK-IN-14 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK-IN-14 is a potent JNK inhibitor with IC50 values of 1.81, 12.7 and 10.5 nM for JNK1, JNK2 and JNK3, respectively. JNK-IN-14 induces early-stage apoptosis. JNK-IN-14 shows cell population arrest at the G2/M phase and slightly inhibits beclin-1 production at K562 leukemia cells relative to SP600125 (HY-12041), showing higher inhibitory ability.[1]

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JNK1 Antibody (YA720) | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

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JNK1 Antibody (YA720) | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

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JNK1 Antibody (YA720) | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

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JNK1+JNK2+JNK3 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

JNK1+JNK2+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK2+JNK3. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.

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JNK1+JNK2+JNK3 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

JNK1+JNK2+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK2+JNK3. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.

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JNK1+JNK2+JNK3 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

JNK1+JNK2+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK2+JNK3. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.

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JNK1+JNK3 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

JNK1+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK3. It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.

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JNK1+JNK3 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

JNK1+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK3. It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.

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JNK1+JNK3 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

JNK1+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK3. It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.

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JNK2 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

JNK2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 46/54 kDa, targeting to JNK2. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

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JNK2 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

JNK2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 46/54 kDa, targeting to JNK2. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

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JNK2 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

JNK2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 46/54 kDa, targeting to JNK2. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

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JNK2-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK2-IN-1 (Compound J27) is a JNK2 inhibitor (Kds: 79.2 μM). JNK2-IN-1 has anti-inflammatory activity. JNK2-IN-1 decreases the release of TNF-α and IL-6 through inhibiting the activation of NF-κB/MAPK pathway. JNK2-IN-1 alleviates the symptoms of LPS-induced acute lung injury (ALI) and sepsis[1].

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JNK3 inhibitor-7 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK3 inhibitor-7 is a potent, orally active and cross the blood-brain barrier JNK3 inhibitor with IC50 values of 53, 973, 1039 nM for JNK3, JNK2, JNK1, respectively. JNK3 inhibitor-7 shows significant neuroprotective effects. JNK3 inhibitor-7 has the potential for the research of Alzheimer’s disease (AD)[1].

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JNK3 inhibitor-8 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

JNK3 inhibitor-8 is a potent, delective, orally active and cross the blood-brain barrier JNK3 inhibitor with IC50 values of 21, 2203, >10000 nM for JNK3, JNK2, JNK1, respectively. JNK3 inhibitor-8 shows significant neuroprotective effects. JNK3 inhibitor-8 has the potential for the research of Alzheimer’s disease (AD)[1].

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