β-Nicotinamide Mononucleotide (β-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase. β-NMN has several beneficial pharmacological activities. Mostly mediated by its involvement in NAD+ biosynthesis, including its role in cellular […]

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands.

γ-Glu-Ala is a dipeptide composed of gamma-glutamate and alanine and is a proteolytic breakdown product of larger proteins. It belongs to the family of N-acyl-alpha amino acids and derivatives, which formed an amide bond with the nitrogen of L-alanine at the γ carboxylic acid moiety of glutamate. γ-Glu-Ala is the natural substrate of CRF21 (γ-Glutamylcyclotransferase, […]

Substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s)

γ-Glu-Glu is a dipeptide, made of two amino acids: gamma-glutamate (γ-Glu) and glutamate (Glu).

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.

This peptide is derived from residues 14-21 of protein kinase C C2 (εPKC C2). This peptide specifically inhibits εPKC by disrupting PKC binding to its receptor, RACK2. εPKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.

ω-Conotoxin GVIA is isolated from the venom of the fish-hunting snail Conus geographus. It has a role as a venom, a neurotoxin, a calcium channel blocker, and a marine metabolite.

Like ω-conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca²⁺ channels. However, ω-conotoxin MVIIC clearly inhibits additional Ca²⁺ channel subtypes in the mammalian central nervous system. Thus, it should become a standard pharmacological reagent for investigating synaptic transmission in the mammalian nervous system.