Creative Biolabs is a leading company of recombinant antibody (rAb) discovery and manufacturing, providing high quality service to customers in academia and industry fields all over the world. Our cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products and extensive service portfolio at the most competitive price.
Company WebsiteLong-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 1, mutation (C.922 ~ 1,032 del; P.308 ~ 344 del) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, then […]
More Information Supplier PageLong-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 1, mutation (G269S, also called G805A) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, then […]
More Information Supplier PageLong-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 1, mutation (G345E, also called G1034A) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, then […]
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Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 1, an autosomal dominant missense mutation (R190Q) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, […]
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Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 1, mutation (T587M) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, then differentiate into cardiac […]
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Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. This disease cell model belongs to long-QT syndrome type 1, mutation (E160fs, also called c.478-2A>T) occur in the KCNQ1 gene. Generating pluripotent stem cells from fibroblasts, then differentiate into cardiac myocytes. This disease cell model provides a platform to explore disease […]
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Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. This disease cell model belongs to long-QT syndrome type 1, mutation (R594Q, also called c.1781G>A) occur in the KCNQ1 gene. Generating pluripotent stem cells from dermal fibroblasts, then differentiate into cardiac myocytes. This disease cell model provides a platform to explore […]
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Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 2, an missense mutation (A561V) occur in the KCNH2 gene. Generating pluripotent stem cells from skin fibroblasts, then differentiate […]
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Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 2, mutation (A614V, also called A614V) occur in the KCNH2 gene. Generating pluripotent stem cells from dermal fibroblasts, then […]
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Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. This disease cell model belongs to long-QT syndrome type 2, an mutation (G1681A, also called p.561A>T) occur in the KCNH2 gene. Generating pluripotent stem cells from skin fibroblasts, […]
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Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
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ADCs cytotoxin, Taltobulin (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
More Information Supplier PageADCs cytotoxin, Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
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ADCs Toxins, Telomestatin is described as an very effective compound with antitumor effects. Telomestatin has been tested to have an IC50 value of 50 nM and therefore it is an very strong telomerase inhibitor.
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Tissue plasminogen activator (tPA). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 […]
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Teriparatide (recombinant human parathyroid hormone) is a potent anabolic agent used in the treatment of osteoporosis. It is manufactured and marketed by Eli Lilly and Company.
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ADCs Toxins, Thiocolchicine is an antimitotic alkaloide. Thiocolchicine is an inhibitor of microtubules by specific binding to tubulin.Thiocolchicine is a topoisomerase I inhibitor.
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Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a […]
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Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
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A recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. Produced in CHO cell culture.
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ADCs Toxins, Triptolin A is described as an specific non-ATP competitve Aurora A kinase inhibitor. Tripolin A doesn`t significantly inhibit Aurora B kinase in mammalian cells. Tripolin A reduces localization of pAurora A on spindle microtubules, affects centrosome integrity, spindle formation and lenght and MT dynamitcs in interphase. Tripolin A is a novel small molecule […]
More Information Supplier PageADCs cytotoxin, Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
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ADCs Toxins, Tubastatin A hydrochloride is a potent and selective inhibitor of HDAC6. IC50=15 nM. Tubastatin A HCl induced the acetylation of [alpha]-tubulin and protected primary cortical neurons against glutathione depletion-induced oxidative stress.
More Information Supplier PageADCs cytotoxin, Tubulysin A(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.
More Information Supplier PageADCs Toxins, Tubulysins show a very high cytotoxic activity against in vitro and in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotheraprutics. Based on the SAR of the tubulysins this class allows for many chemical conjugation and […]
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Low molecular weight form of human urokinase, that consists of an A chain of 2,000 daltons linked by a sulfhydryl bond to a B chain of 30,400 daltons. Recombinant urokinase plasminogen activator
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ADCs linker, Val-Cit-PAB is an precursor for making MC-Val-Cit-PAB.
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ADCs linker, Val-cit-PAB-OH is an precursor for making MC-Val-Cit-PAB.
More Information Supplier PageLinker-Toxin SET, Vc-MMAD consists the ADCs linker(Val-Cit) and potent tubulin inhibitor (MMAD), Vc-MMAD is an antibody drug conjugate.
More Information Supplier PageLinker-Toxin SET, VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
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