AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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AMC Standard Solution 100 µl  | Purity Not Available

AdipoGen Life Sciences

A fluorogenic standard useful for quantitating assays monitoring amido-4-methylcoumarin (AMC) release. These include ubiquitin-AMC, SUMO-1-AMC, NEDD8-AMC, ISG15-AMC and proteasome substrates. The concentration of the AMC released can be calculated from a standard curve prepared with AMC standards.

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AMCA-H 100 mg  | >90%

AdipoGen Life Sciences

AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke’s shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and […]

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AMCA-H 500 mg  | >90%

AdipoGen Life Sciences

AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke’s shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and […]

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AMCA-H 2 g  | >90%

AdipoGen Life Sciences

AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke’s shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and […]

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AMCA-H N-succinimidyl ester 25 mg  | >90%

AdipoGen Life Sciences

AMCA-H NHS ester reacts with primary amine groups on antibodies, proteins, peptides and other biomolecules at pH 7.0-9.0. Suitable for labeling lysyl residues in proteins (Ex/Em: 353/455nm).

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AMCA-H N-succinimidyl ester 100 mg  | >90%

AdipoGen Life Sciences

AMCA-H NHS ester reacts with primary amine groups on antibodies, proteins, peptides and other biomolecules at pH 7.0-9.0. Suitable for labeling lysyl residues in proteins (Ex/Em: 353/455nm).

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AMI-1 5 mg  | >99%

AdipoGen Life Sciences

Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8 µM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0 µM).

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AMI-1 25 mg  | >99%

AdipoGen Life Sciences

Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8 µM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0 µM).

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Amicarbazone 50 mg  | >98%

AdipoGen Life Sciences

Herbicide with a broad spectrum of weed control. Potent inhibitor of photosynthetic electron transport, inducing chlorophyll fluorescence and interrupting oxygen evolution via binding to the Qb domain of photosystem II (PSII). Compound can be used as analytical reference material.

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Amicarbazone 100 mg  | >98%

AdipoGen Life Sciences

Herbicide with a broad spectrum of weed control. Potent inhibitor of photosynthetic electron transport, inducing chlorophyll fluorescence and interrupting oxygen evolution via binding to the Qb domain of photosystem II (PSII). Compound can be used as analytical reference material.

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Amidepsine A 1 mg  | >95%

AdipoGen Life Sciences

Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

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Amidepsine A 2.5 mg  | >95%

AdipoGen Life Sciences

Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

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Amidepsine D 1 mg  | >95%

AdipoGen Life Sciences

Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

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Amidepsine D 2.5 mg  | >95%

AdipoGen Life Sciences

Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

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Amlexanox 10 mg  | >98%

AdipoGen Life Sciences

Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to the synthesis of functional full-length proteins in an efficient manner. Selective inhibitor of TANK-binding Kinase 1 (TBK1) and IKKepsilon. Reversibly lowers […]

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Amlexanox 50 mg  | >98%

AdipoGen Life Sciences

Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to the synthesis of functional full-length proteins in an efficient manner. Selective inhibitor of TANK-binding Kinase 1 (TBK1) and IKKepsilon. Reversibly lowers […]

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Amorfrutin A 500 µg  | ≥97%

AdipoGen Life Sciences

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows […]

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Amorfrutin B 500 µg  | >97%

AdipoGen Life Sciences

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. The binding affinity constant to PPARgamma is 12 times lower than Amorfrutin A (Prod. No. AG-CN2-0462). Glucose-lowering agent. […]

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AMQI 100 mg  | >98%

AdipoGen Life Sciences

Fluorogenic substrate for cholinesterase. Non-fluorescent 7-acetoxy-1-methyl quinolinium iodide is hydrolysed to the highly fluorescent 7-hydroxy-1-methyl quinolinium iodide.

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AMQI 1 g  | >98%

AdipoGen Life Sciences

Fluorogenic substrate for cholinesterase. Non-fluorescent 7-acetoxy-1-methyl quinolinium iodide is hydrolysed to the highly fluorescent 7-hydroxy-1-methyl quinolinium iodide.

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Anacardic acid 5 mg  | >98%

AdipoGen Life Sciences

Potent histone acetyltransferase (HAT) inhibitor. Antibacterial. SUMOylation inhibitor. Lipoxygenase inhibitor. NF-kappaB inhibitor. Anti-tumor compound. Anti-inflammatory. Apoptosis inducer. Antiproliferative.

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Anacardic acid 25 mg  | >98%

AdipoGen Life Sciences

Potent histone acetyltransferase (HAT) inhibitor. Antibacterial. SUMOylation inhibitor. Lipoxygenase inhibitor. NF-kappaB inhibitor. Anti-tumor compound. Anti-inflammatory. Apoptosis inducer. Antiproliferative.

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Andrastin A 250 µg  | >95%

AdipoGen Life Sciences

Mycotoxin. Protein farnesyltransferase (PFTase) inhibitor. Anti-cancer compound. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells.

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Andrastin A 1 mg  | >95%

AdipoGen Life Sciences

Mycotoxin. Protein farnesyltransferase (PFTase) inhibitor. Anti-cancer compound. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells.

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Anthralin 1 g  | >98%

AdipoGen Life Sciences

Anthralin is a leukotriene biosynthesis inhibitor. It inhibits LTB4 omega-oxidation and disrupts mitochondria function. Anthralin is used in the treatment of psoriasis, as a fungicide, in the treatment of ringworm infections and in chronic dermatoses. It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of […]

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Anthralin 5 g  | >98%

AdipoGen Life Sciences

Anthralin is a leukotriene biosynthesis inhibitor. It inhibits LTB4 omega-oxidation and disrupts mitochondria function. Anthralin is used in the treatment of psoriasis, as a fungicide, in the treatment of ringworm infections and in chronic dermatoses. It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of […]

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Antipain . dihydrochloride 5 mg  | >97%

AdipoGen Life Sciences

Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after […]

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Antipain . dihydrochloride 25 mg  | >97%

AdipoGen Life Sciences

Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after […]

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Apcin 5 mg  | >95%

AdipoGen Life Sciences

Cell permeable compound capable of slowing anaphase-promoting complex/cyclosome (APC/C)-dependent proteolysis. Inhibitor of the ubiquitin ligase activity of the APC/C by inhibiting substrate binding to Cdc20. Distinct mechanism of action than proTAME. Blocks mitotic exit only modestly when used alone in cultured cells. A strong synergistic effect is observed when Apcin and proTAME are used simultaneously, […]

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Aphidicolin 17-acetate 250 µg  | >96%

AdipoGen Life Sciences

Phytotoxin (inhibits root growth of seeding). Specific inhibitor of eukaryotic DNA polymerase alpha and DNA synthesis (competition with dCTP).

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Aphidicolin-3alpha,18-acetonide 250 µg  | >98%

AdipoGen Life Sciences

Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html . Mycotoxin. So far no comparison to aphidicolin’s biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.

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Aphidicolin-3alpha,18-acetonide 1 mg  | >98%

AdipoGen Life Sciences

Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html . Mycotoxin. So far no comparison to aphidicolin’s biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.

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Apicidin 1 mg  | >98%

AdipoGen Life Sciences

Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells. Promotes either self-renewal or differentiation […]

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Apicidin 5 mg  | >98%

AdipoGen Life Sciences

Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells. Promotes either self-renewal or differentiation […]

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AQC 50 mg  | >95%

AdipoGen Life Sciences

Suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection.

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AQC 250 mg  | >95%

AdipoGen Life Sciences

Suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection.

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Aranciamycin 500 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Similar to steffimycin. Active against Gram-positive bacteria. Clostridium histolyticum collagenase inhibitor. Antitumor compound.

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