AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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Puromycin . dihydrochloride 1 g  | >98%

AdipoGen Life Sciences

Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol […]

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Pyranonigrin A 250 µg  | >95%

AdipoGen Life Sciences

Antioxidant. Radical scavenging activity towards DPPH and superoxide. Shows a suppressive effect on the expression of vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs) induced by tumor necrosis factor-alpha (TNF-alpha). Insecticidal agent.

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Pyranonigrin A 1 mg  | >95%

AdipoGen Life Sciences

Antioxidant. Radical scavenging activity towards DPPH and superoxide. Shows a suppressive effect on the expression of vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs) induced by tumor necrosis factor-alpha (TNF-alpha). Insecticidal agent.

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Pyributicarb 100 mg  | >98%

AdipoGen Life Sciences

Thiocarbamate herbicide with fungicidal activity. Inhibits 4-hydroxyphenyl-pyruvatedioxygenase (4-HPPD) in plants that causes bleaching. And targets squalene-epoxidase in sterol biosynthesis in fungus. Compound can be used as analytical reference material.

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Pyributicarb 250 mg  | >98%

AdipoGen Life Sciences

Thiocarbamate herbicide with fungicidal activity. Inhibits 4-hydroxyphenyl-pyruvatedioxygenase (4-HPPD) in plants that causes bleaching. And targets squalene-epoxidase in sterol biosynthesis in fungus. Compound can be used as analytical reference material.

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Pyridomycin 1 mg  | >98%

AdipoGen Life Sciences

Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria.

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Pyridomycin 2.5 mg  | >98%

AdipoGen Life Sciences

Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria.

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Pyridoxatin 250 µg  | >95%

AdipoGen Life Sciences

Antibiotic. Free radical scavenger. Lipid peroxidation inhibitor. Antimicrobial activity against Candida albicans. Gelatinase A (MMP-2) inhibitor. Anticancer. Cytotoxic. DNA synthesis inhibitor.

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Pyridoxatin 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Free radical scavenger. Lipid peroxidation inhibitor. Antimicrobial activity against Candida albicans. Gelatinase A (MMP-2) inhibitor. Anticancer. Cytotoxic. DNA synthesis inhibitor.

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Pyripyropene A 500 µg  | >95%

AdipoGen Life Sciences

Antibiotic. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2). Anti-angiogenic. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities..

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Pyripyropene A 250 µg  | >95%

AdipoGen Life Sciences

Antibiotic. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2). Anti-angiogenic. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities..

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Pyripyropene A 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2). Anti-angiogenic. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities..

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Pyrithiobac 100 mg  | >98%

AdipoGen Life Sciences

Aromatic acid herbicide. Mode of action is through inhibition of acetolactate synthase (ALS; acetohydroxyacid synthase; AHAS). Compound can be used as analytical reference material.

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Pyrithiobac 250 mg  | >98%

AdipoGen Life Sciences

Aromatic acid herbicide. Mode of action is through inhibition of acetolactate synthase (ALS; acetohydroxyacid synthase; AHAS). Compound can be used as analytical reference material.

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PyTC2 100 mg  | >85%

AdipoGen Life Sciences

Fluorescent probe with high quantum efficiency, exhibiting single exponential decay kinetics. The radiative fluorescence lifetime is almost constant and independent on molecular surroundings allowing this probe to be utilized in a range of microsurroundings with exciting radiation at a constant wavelength (in the blue spectral range). Its fluorescence emission demonstrates a large solvatochromic shift which […]

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PyTC2 1 g  | >85%

AdipoGen Life Sciences

Fluorescent probe with high quantum efficiency, exhibiting single exponential decay kinetics. The radiative fluorescence lifetime is almost constant and independent on molecular surroundings allowing this probe to be utilized in a range of microsurroundings with exciting radiation at a constant wavelength (in the blue spectral range). Its fluorescence emission demonstrates a large solvatochromic shift which […]

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Q-VD-OPh 1 mg  | >95%

AdipoGen Life Sciences

Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]

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Q-VD-OPh 5 mg  | >95%

AdipoGen Life Sciences

Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]

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Q-VD-OPh MultiPack 3 x 1 mg  | >95%

AdipoGen Life Sciences

Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]

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Q-VE-OPh (Negative Control for Q-VD-OPh) 1 mg  | >95%

AdipoGen Life Sciences

Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh (Prod. No. AG-CP3-0006). Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies.

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Quercetin . dihydrate 1 g  | >95%

AdipoGen Life Sciences

Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase (Trk), mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C (PKC). DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty […]

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Quercetin . dihydrate 5 g  | >95%

AdipoGen Life Sciences

Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase (Trk), mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C (PKC). DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty […]

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Quinine (anhydrous) 5 g  | >98%

AdipoGen Life Sciences

Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic (fever-reducing), antimalarial, analgesic […]

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Quinine (anhydrous) 50 g  | >98%

AdipoGen Life Sciences

Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic (fever-reducing), antimalarial, analgesic […]

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Quinine (anhydrous) 500 g  | >98%

AdipoGen Life Sciences

Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic (fever-reducing), antimalarial, analgesic […]

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Quinolactacin A 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Acetylcholinesterase (AChE) inhibitor. Anti-inflammatory compound. Tumor necrosis factor (TNF) inhibitor.

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Quinolactacin A 5 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Acetylcholinesterase (AChE) inhibitor. Anti-inflammatory compound. Tumor necrosis factor (TNF) inhibitor.

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R-848 5 mg  | >98%

AdipoGen Life Sciences

Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the […]

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R-848 25 mg  | >98%

AdipoGen Life Sciences

Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the […]

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R-BAIBA 100 mg  | >99%

AdipoGen Life Sciences

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains […]

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R-BAIBA 500 mg  | >99%

AdipoGen Life Sciences

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains […]

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Radicicol 1 mg  | >99%

AdipoGen Life Sciences

Antibiotic. Protein tyrosine kinase inhibitor. Has antifungal, antimalarial, antiangiogenic (in vivo), anti-inflammatory and antiviral activity. Cyclooxygenase-2 (COX-2) expression inhibitor without affecting COX-1 expression in LPS-stimulated macrophages. Induces the differentiation of HL-60 cells into macrophages. Potent HSP90 inhibitor. Anticancer compound. In vivo Rad/Raf interaction inhibitor. Inhibitor of AP-1-, NF-kappaB- and serum response factor (SRF)-mediated transcription. Suppresses […]

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Radicicol 5 mg  | >99%

AdipoGen Life Sciences

Antibiotic. Protein tyrosine kinase inhibitor. Has antifungal, antimalarial, antiangiogenic (in vivo), anti-inflammatory and antiviral activity. Cyclooxygenase-2 (COX-2) expression inhibitor without affecting COX-1 expression in LPS-stimulated macrophages. Induces the differentiation of HL-60 cells into macrophages. Potent HSP90 inhibitor. Anticancer compound. In vivo Rad/Raf interaction inhibitor. Inhibitor of AP-1-, NF-kappaB- and serum response factor (SRF)-mediated transcription. Suppresses […]

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Rapamycin 100 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the […]

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Rapamycin 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the […]

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Rapamycin 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the […]

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Rapamycin 25 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the […]

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Raptinal 1 mg  | >98%

AdipoGen Life Sciences

Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis. Induces cell death against various cancer and non-cancerous cell lines with 24 hour IC50 values between 0.7-3.4µM indicating activity across a wide range of cell […]

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Raptinal 5 mg  | >98%

AdipoGen Life Sciences

Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis. Induces cell death against various cancer and non-cancerous cell lines with 24 hour IC50 values between 0.7-3.4µM indicating activity across a wide range of cell […]

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Raptinal 25 mg  | >98%

AdipoGen Life Sciences

Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis. Induces cell death against various cancer and non-cancerous cell lines with 24 hour IC50 values between 0.7-3.4µM indicating activity across a wide range of cell […]

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Rebeccamycin 250 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).

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