AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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Lasalocid A sodium salt 50 mg  | >97%

AdipoGen Life Sciences

Ionophore. Potent antibacterial agent and a coccidiostat. Able to form neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also larger organic cations, like protonated dopamine.

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Lasalocid A sodium salt 250 mg  | >97%

AdipoGen Life Sciences

Ionophore. Potent antibacterial agent and a coccidiostat. Able to form neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also larger organic cations, like protonated dopamine.

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Latrunculin A 100 µg  | >96%

AdipoGen Life Sciences

Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion. Acts via a different mechanism than cytochalasins.

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Latrunculin A 500 µg  | >96%

AdipoGen Life Sciences

Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion. Acts via a different mechanism than cytochalasins.

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Latrunculin B 1 mg  | >96%

AdipoGen Life Sciences

Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Less potent than Latrunculin A (Prod. No. AG-CN2-0027 http://www.adipogen.com/ag-cn2-0027/latrunculin-a.html ). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies. Acts […]

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Laurdan 50 mg  | ≥98%

AdipoGen Life Sciences

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of […]

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Laurdan 250 mg  | >97%

AdipoGen Life Sciences

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of […]

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Laurdan 1 g  | >97%

AdipoGen Life Sciences

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of […]

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Ledol 500 mg  | >95%

AdipoGen Life Sciences

Toxic sesquiterpenoid. Exhibits expectorant and antitussive effect. Reported to increase blood pressure. Antifungal compound.

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Ledol 1 g  | >95%

AdipoGen Life Sciences

Toxic sesquiterpenoid. Exhibits expectorant and antitussive effect. Reported to increase blood pressure. Antifungal compound.

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Leucettine L41 1 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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Leucettine L41 5 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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Leucettine L41 25 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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Leupeptin . hemisulfate 5 mg  | >97%

AdipoGen Life Sciences

Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant […]

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Leupeptin . hemisulfate 25 mg  | >97%

AdipoGen Life Sciences

Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant […]

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Leupeptin . hemisulfate 100 mg  | >97%

AdipoGen Life Sciences

Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant […]

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Linagliptin 10 mg  | >98%

AdipoGen Life Sciences

Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.

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Linagliptin 50 mg  | >98%

AdipoGen Life Sciences

Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.

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Lovastatin 5 mg  | >98%

AdipoGen Life Sciences

Statin compound. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Causes cell cycle arrest in G1 and G2/M phases through modulation of proteasome in cancer cell lines. Smooth muscle […]

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Lovastatin 25 mg  | >98%

AdipoGen Life Sciences

Statin compound. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Causes cell cycle arrest in G1 and G2/M phases through modulation of proteasome in cancer cell lines. Smooth muscle […]

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Loxoribine 5 mg  | >97%

AdipoGen Life Sciences

Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in […]

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Loxoribine 25 mg  | >97%

AdipoGen Life Sciences

Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in […]

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Lucigenin 2 g  | >98%

AdipoGen Life Sciences

Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

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Lucigenin 10 g  | >98%

AdipoGen Life Sciences

Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

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Luisol A 1 mg  | >98%

AdipoGen Life Sciences

Shows weak cytotoxic activity against different tumor cell lines. Has antiparasitic activity.

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Luisol A 5 mg  | >98%

AdipoGen Life Sciences

Shows weak cytotoxic activity against different tumor cell lines. Has antiparasitic activity.

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Luminol 25 g  | >97%

AdipoGen Life Sciences

Very efficient and commonly used chemiluminiscent compound in many applications. Cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation. Oxidizing agents capable of initiating this particular reaction are nitrogen dioxide, PAN, hydrogen peroxide, ozone and other atmospheric oxidants. As an example, HRP combined with hydrogen peroxide as an activator, causes luminescent peroxidation of luminol. This reaction […]

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Luminol 100 g  | >97%

AdipoGen Life Sciences

Very efficient and commonly used chemiluminiscent compound in many applications. Cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation. Oxidizing agents capable of initiating this particular reaction are nitrogen dioxide, PAN, hydrogen peroxide, ozone and other atmospheric oxidants. As an example, HRP combined with hydrogen peroxide as an activator, causes luminescent peroxidation of luminol. This reaction […]

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Lupallene B 1 mg  | >97%

AdipoGen Life Sciences

Unique fungal allene derivative. Similar to A 82775C and iso-A 82775C. Biological activity not tested yet.

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Lupallene B 5 mg  | >97%

AdipoGen Life Sciences

Unique fungal allene derivative. Similar to A 82775C and iso-A 82775C. Biological activity not tested yet.

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Lupallene D 1 mg  | >97%

AdipoGen Life Sciences

Unique fungal allene derivative. Similar to A 82775C and iso-A 82775C. Biological activity not tested yet.

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Lupallene D 5 mg  | >97%

AdipoGen Life Sciences

Unique fungal allene derivative. Similar to A 82775C and iso-A 82775C. Biological activity not tested yet.

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Luteolin 5 mg  | >98%

AdipoGen Life Sciences

Anticancer and antimetastatic. alpha-Glucosidase inhibitor. Topoisomerase I Inhibitor. Apoptosis inducer. Anti-inflammatory. 15-Lipoxygenase (15-LOX) inhibitor. IL-6 production inhibitor. Fatty acid synthase (FAS) inhibitor. Antioxidant. Free radical scavenger. Antiadipogenic. PPAR-gamma inhibitor. Neuroprotective. Monoamine transporter activator. Inhibitor of phosphodiesterases 1-5 (PDE1-5). PKC(epsilon) and Src kinase inhibitor. HDAC inhibitor. Autophagy modulator Phosphatidylinositol 3-kinase (PI3K) / Akt signaling inhibitor. p90 […]

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Luteolin 25 mg  | >98%

AdipoGen Life Sciences

Anticancer and antimetastatic. alpha-Glucosidase inhibitor. Topoisomerase I Inhibitor. Apoptosis inducer. Anti-inflammatory. 15-Lipoxygenase (15-LOX) inhibitor. IL-6 production inhibitor. Fatty acid synthase (FAS) inhibitor. Antioxidant. Free radical scavenger. Antiadipogenic. PPAR-gamma inhibitor. Neuroprotective. Monoamine transporter activator. Inhibitor of phosphodiesterases 1-5 (PDE1-5). PKC(epsilon) and Src kinase inhibitor. HDAC inhibitor. Autophagy modulator Phosphatidylinositol 3-kinase (PI3K) / Akt signaling inhibitor. p90 […]

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Luteoreticulin 500 µg  | >98%

AdipoGen Life Sciences

Nitrophenyl pyranone derivative related to aureothin (Prod. No. BVT-0303 http://www.adipogen.com/bvt-0303/aureothin.html ). Insecticidal and nematocidal compound. Metabolites within this product class show pronounced antitumor and immunosuppressive activity.

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Luteoreticulin 1 mg  | >98%

AdipoGen Life Sciences

Nitrophenyl pyranone derivative related to aureothin (Prod. No. BVT-0303 http://www.adipogen.com/bvt-0303/aureothin.html ). Insecticidal and nematocidal compound. Metabolites within this product class show pronounced antitumor and immunosuppressive activity.

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LY-294,002 1 mg  | >99%

AdipoGen Life Sciences

Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

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LY-294,002 5 mg  | >99%

AdipoGen Life Sciences

Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

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LY-294,002 25 mg  | >99%

AdipoGen Life Sciences

Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

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LY-333,531 . hydrochloride 1 mg  | >98%

AdipoGen Life Sciences

Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.

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LY-333,531 . hydrochloride 5 mg  | >98%

AdipoGen Life Sciences

Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.

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LysoGlow84 1 mg  | >98%

AdipoGen Life Sciences

Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric […]

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Lysolipin I 500 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Glycopeptide synthesis inhibitor. Antibacterial, antifungal and anticoccidial. Cytotoxic.

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