17-DMAG
Less toxic, more potent synthetic derivative of geldanamycin (Prod. No. BVT-0196). Angiogenesis inhibitor. Heat shock protein 90 (HSP90) inhibitor. Apoptosis inducer. Shows higher antitumor activity than 17-AAG (Prod. No. BVT-0244).
| Catalog Number | BVT-0255-M001 |
| Alternative Name(s) | NSC 707545; 17-[2-(Dimethylamino)ethyl]amino-17-desmethoxygeldanamycin |
| Research Area | Apoptosis, Cancer, Cell Death, Natural Products |
| Molecular Formula | C32H48N4O8 |
| CAS# | 467214-20-6 |
| Purity | >98% |
| Inchi | InChI=1S/C32H48N4O8/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40)/b11-9-,19-10+,21-16+/t18-,20+,25+,26+,28-,30+/m1/s1 |
| Inchi Key | KUFRQPKVAWMTJO-LMZWQJSESA-N |
| SMILES | [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](C=CC)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@@]1([H])OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@H](CC)[C@H](O)[C@H](C)CC(C)=CC=C[C@@H]1OC |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/bvt-0255/17-dmag.html |