Sterigmatocystin
Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver. Induces sister chromatid exchanges in murine bone marrow cells.
| Catalog Number | BVT-0171-M005 |
| Alternative Name(s) | NSC 201423; NSC 204985 |
| Research Area | Apoptosis, Cancer, Metabolism, Natural Products |
| Molecular Formula | C18H12O6 |
| CAS# | 10048-13-2 |
| Purity | >98% |
| Inchi | InChI=1S/C18H12O6/c1-21-11-7-12-13(8-5-6-22-18(8)24-12)17-15(11)16(20)14-9(19)3-2-4-10(14)23-17/h2-8,18-19H,1H3/t8-,18+/m0/s1 |
| Inchi Key | UTSVPXMQSFGQTM-DCXZOGHSSA-N |
| SMILES | [H][C@]12OC=C[C@@]1([H])C1=C3OC4=C(C(O)=CC=C4)C(=O)C3=C(OC)C=C1O2 |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/bvt-0171/sterigmatocystin.html |