Kirromycin
Antibiotic. Member of the elfermycin group. Antibacterial. Protein biosynthesis inhibitor. Specifically interacts with the bacterial elongation factor EF-Tu and prevents the release of EF-Tu from the bacterial ribosome after GTP hydrolysis. In the absence of ribosomes it induces EF-Tu-dependent hydrolysis of GTP. Animal growth promoter used in poultry breeding.
| Catalog Number | BVT-0157-M001 |
| Alternative Name(s) | Mocimycin; Delvomycin; MYC 8003; NSC 316094 |
| Research Area | Antibiotic, Cancer, Cell Death, Inflammation, Natural Products |
| Molecular Formula | C43H60N2O12 |
| CAS# | 50935-71-2 |
| Purity | >96% |
| Inchi | InChI=1S/C43H60N2O12/c1-9-11-13-21-31-42(6,7)38(50)39(51)43(54,57-31)28(10-2)40(52)44-23-17-16-19-26(4)36(55-8)27(5)37-35(49)34(48)30(56-37)20-15-12-14-18-25(3)33(47)32-29(46)22-24-45-41(32)53/h9,11-22,24,27-28,30-31,34-39,48-51,54H,10,23H2,1-8H3,(H,44,52)(H2,45,46,53)/b11-9-,14-12+,17-16+,20-15+,21-13+,25-18+,26-19+/t27-,28-,30-,31+,34+,35+,36-,37+,38+,39-,43-/m1/s1 |
| Inchi Key | HMSYAPGFKGSXAJ-PAHGNTJYSA-N |
| SMILES | [H][C@@]1(O[C@@]([H])([C@H](C)[C@H](OC)C(C)=CC=CCNC(=O)[C@@H](CC)C2(O)OC(C=CC=C/C)C(C)(C)C(O)C2O)[C@@H](O)[C@H]1O)C=CC=CC=C(/C)C(=O)C1=C(O)C=CNC1=O |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/bvt-0157/kirromycin.html |