Bafilomycin C1
Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and anthelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer.
Catalog Number | BVT-0068-M001 |
Alternative Name(s) | L-681,110A1; 2-Demethyl-2-methoxy-24-methyl-hygrolidin |
Research Area | Antibiotic, Autophagy, Bone Research, Immunology, Metabolism, Neurobiology |
Molecular Formula | C39H60O12 |
CAS# | 88979-61-7 |
Purity | >98% |
Inchi | InChI=1S/C39H60O12/c1-21(2)36-26(7)31(49-33(42)16-15-32(40)41)20-39(46,51-36)28(9)35(44)27(8)37-29(47-10)14-12-13-22(3)17-24(5)34(43)25(6)18-23(4)19-30(48-11)38(45)50-37/h12-16,18-19,21,24-29,31,34-37,43-44,46H,17,20H2,1-11H3,(H,40,41)/b14-12-,16-15+,22-13+,23-18+,30-19-/t24-,25+,26-,27-,28-,29-,31+,34-,35+,36+,37+,39+/m0/s1 |
Inchi Key | WUDBXVQNMOTFEE-WSNZTHDZSA-N |
SMILES | [H][C@@]1(OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)C=CC(O)=O)[C@H](C)[C@H](O1)C(C)C |
Size | 1 mg |
Supplier Page | http://www.adipogen.com/bvt-0068/bafilomycin-c1.html |