Hurghadolide A
Cell permeable dilactone macrolide. Potent cytotoxic compound against selected cancer cells. Depolymerizes actin filaments (F-actin). Potent disruptor of cellular microfilaments. Antifungal against Candida albicans.
| Catalog Number | AG-CN2-0508-C010 |
| Research Area | Apoptosis, Cancer, Cell Death, Immunology, Natural Products |
| Molecular Formula | C76H130O20 |
| CAS# | 877822-91-8 |
| Purity | >98% |
| Inchi | InChI=1S/C76H130O20/c1-43-23-28-55(77)35-57-19-17-21-59(93-57)39-70(90-16)50(8)66(80)42-68(82)52(10)75(54(12)73(85)45(3)27-31-62-38-64(88-14)34-48(6)92-62)96-76(86)46(4)25-29-56(78)36-58-20-18-22-60(94-58)40-69(89-15)49(7)65(79)41-67(81)51(9)74(95-71(83)32-24-43)53(11)72(84)44(2)26-30-61-37-63(87-13)33-47(5)91-61/h17-20,23-25,32,44-45,47-70,72-75,77-82,84-85H,21-22,26-31,33-42H2,1-16H3/b32-24+,43-23+,46-25+/t44-,45-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57+,58+,59-,60-,61-,62-,63?,64?,65-,66-,67+,68+,69?,70?,72-,73-,74-,75-/m0/s1 |
| Inchi Key | PBOKTYWXRURPFG-BKSSZMRDSA-N |
| SMILES | O[C@H]([C@H](C)[C@H]1OC(/C=C/C(C)=C/C[C@H](O)C[C@H]2C=CC[C@@H](C[C@H](OC)[C@H]([C@@H](O)C[C@@H](O)[C@@H]([C@@H]([C@@H](C)[C@@H](O)[C@@H](C)CC[C@H]3C[C@H](OC)C[C@H](C)O3)OC(/C(C)=C/C[C@H](O)C[C@@H]4O[C@H](C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@@H]1C)CC=C4)=O)C)C)O2)=O)[C@@H](C)CC[C@@H]5O[C@@H](C)C[C@@H](OC)C5 |
| Size | 10 µg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0508/hurghadolide-a.html |