Hymenidin
Inhibitor of CDK5/p25 (IC50=4µM) and GSK-3beta (IC50=12µM). Potentially useful in neuronal diseases research. Antagonist of serotonergic receptors. Shown to reduce voltage-dependent calcium elevation. Moderate anticancer compound. Inhibits cell growth in a panel of cancer cell lines at low µM range. Antiprotozoal agent. Antibacterial. Plays a role in the sponge antibacterial defense.
| Catalog Number | AG-CN2-0503-M001 |
| Alternative Name(s) | N-[(2E)-3-(2-Amino-1H-imidazol-5-yl)prop-2-en-1-yl]-4-bromo-1H-pyrrole-2-carboxamide; Hymenidine; 2-Debromooroidin |
| Research Area | Cancer, Inflammation, Natural Products, Neurobiology, Neurodegenerative Disease |
| Molecular Formula | C11H12BrN5O . H2O |
| CAS# | 107019-95-4 |
| Purity | >97% |
| Inchi | InChI=1S/C11H12BrN5O/c12-7-4-9(15-5-7)10(18)14-3-1-2-8-6-16-11(13)17-8/h1-2,4-6,15H,3H2,(H,14,18)(H3,13,16,17)/b2-1+ |
| Inchi Key | KHJREOQCERRAME-OWOJBTEDSA-N |
| SMILES | O=C(NC/C=C/C1=CN=C(N)N1)C2=CC(Br)=CN2 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0503/hymenidin.html |