Agelasine D

Antifouling compound. Antimycobacterial and antibacterial agent. Exerts its antibacterial effect by inhibiting enzyme BCG 3185c, a suspected dioxygenase thereby disrupting bacterial homeostasis. Associated with contractive responses of smooth muscles and inhibition of Na+/K+ ATPase. Cytotoxic/Antineoplastic agent. Found to exhibit inhibitory activity against several cancer cell lines, including the drug resistant renal cancer cell line (ACHN). Suppressor of RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1, NF-kappaB and ERK. Antiprotozoal compound.

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Catalog Number	AG-CN2-0492-M001
Alternative Name(s)	(+)-Agelasine D
Research Area	Antibiotic, Biochemicals, Cancer, Natural Products
Molecular Formula	C26H40N5
CAS#	92664-80-7
Purity	>97%
Inchi	InChI=1S/C26H41N5/c1-18(12-15-31-17-30(6)24-22(31)23(27)28-16-29-24)8-10-20-19(2)9-11-21-25(3,4)13-7-14-26(20,21)5/h12,16,20-21H,2,7-11,13-15,17H2,1,3-6H3,(H2,27,28,29)/p+1/b18-12+/t20-,21-,26+/m0/s1
Inchi Key	SHVHRNDHUVXXIF-XGBZQHFCSA-O
SMILES	C/C(CC[C@H]1C(CC[C@]2([H])[C@]1(C)CCCC2(C)C)=C)=CC[NH]3CN(C)C4=C3C(N)=NC=N4
Size	1 mg
Supplier Page	http://www.adipogen.com/ag-cn2-0492/agelasine-d.html