Jak/Src inhibitor 1 . hydrochloride
Anticancer compound. Potent antiproliferative agent in vitro and in vivo. Combined inhibitor of pSTAT3 proteins such as JAK, SRC, ABL and class III/V receptor tyrosine kinases (RTK), including FLT3, c-KIT, CSF1-R, PDGFRs and VEGFRs, in nanomolar range.
| Catalog Number | AG-CR1-3647-M001 |
| Alternative Name(s) | Debio 0617B hydrochloride; N-(4-Chloro-3-(2-((4-(methyl-carbamoyl)phenyl)amino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)phenyl)-4-(trifluoromethyl)picolinamide |
| Research Area | Biochemicals, Cancer, Immunology, Stem Cell Research |
| Molecular Formula | C28H23ClF3N7O2 . HCl |
| CAS# | 1332329-27-7 (parent) |
| Purity | >97% |
| Inchi | InChI=1S/C28H23ClF3N7O2.ClH/c1-33-25(40)16-2-4-19(5-3-16)37-27-35-14-17-15-39(11-9-22(17)38-27)24-13-20(6-7-21(24)29)36-26(41)23-12-18(8-10-34-23)28(30,31)32;/h2-8,10,12-14H,9,11,15H2,1H3,(H,33,40)(H,36,41)(H,35,37,38);1H |
| Inchi Key | VQUNOHCOLZKQJY-UHFFFAOYSA-N |
| SMILES | O=C(NC)C(C=C1)=CC=C1NC2=NC=C3C(CCN(C4=CC(NC(C5=NC=CC(C(F)(F)F)=C5)=O)=CC=C4Cl)C3)=N2.Cl |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3647/jak-src-inhibitor-1-hydrochloride.html |