MMG-0358
Potent triazole IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor. Has IC50 values of 2nM in a cellular assay on mIDO1, 80nM in a cellular assay on hIDO1, 330nM in an enzymatic assay on hIDO1 at pH 6.5 and 71nM in an enzymatic assay on hIDO1 at pH 7.4. Shown to be active in vivo.
| Catalog Number | AG-CR1-3630-M005 |
| Alternative Name(s) | 4-Chloro-2-(1H-1,2,3-triazol-5-yl)phenol |
| Research Area | Biochemicals, Cancer, Metabolism |
| Molecular Formula | C8H6ClN3O |
| CAS# | 1378976-02-3 |
| Purity | >98% |
| Inchi | InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) |
| Inchi Key | NBDFMTBYKCBTSW-UHFFFAOYSA-N |
| SMILES | OC1=C(C=C(Cl)C=C1)C1=CN=NN1 |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3630/mmg-0358.html |