Troglitazone
Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Anti-inflammatory. Inhibits vascular smooth muscle cell (VSMC) migration.
| Catalog Number | AG-CR1-3565-M005 |
| Alternative Name(s) | 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione; Romglizone; BRN 4338399; CS-045; CI-991; GR 92132X |
| Research Area | Biochemicals, Cancer, Inflammation, Metabolism |
| Molecular Formula | C24H27NO5S |
| CAS# | 97322-87-7 |
| Purity | >98% |
| Inchi | InChi=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28) |
| Inchi Key | GXPHKUHSUJUWKP-UHFFFAOYSA-N |
| SMILES | CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3565/troglitazone.html |