GANT61
Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription. Sonic hedgehog (Shh) signaling pathway inhibitor, downstream of SMO and SUFU. Displays antiproliferative and antitumor activity in vitro and in vivo. Apoptosis inducer.
| Catalog Number | AG-CR1-3561-M001 |
| Alternative Name(s) | NSC 136476; 2,2’-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine |
| Research Area | Apoptosis, Biochemicals, Cancer, Cell Death, Immunology, Stem Cell Research |
| Molecular Formula | C27H35N5 |
| CAS# | 500579-04-4 |
| Purity | >98% |
| Inchi | InChI=1S/C27H35N5/c1-29(2)25-12-7-5-10-23(25)20-31-18-9-19-32(27(31)22-14-16-28-17-15-22)21-24-11-6-8-13-26(24)30(3)4/h5-8,10-17,27H,9,18-21H2,1-4H3 |
| Inchi Key | KVQOGDQTWWCZFX-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC=CC=C1CN1CCCN(CC2=C(C=CC=C2)N(C)C)C1C1=CC=NC=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3561/gant61.html |