PJ-34
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells.
Catalog Number | AG-CR1-0100-M001 |
Alternative Name(s) | N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide . HCl |
Research Area | Biochemicals, Cancer, Inflammation |
Molecular Formula | C17H17N3O2 . HCl |
CAS# | 344458-15-7 |
Purity | >98% |
Inchi | InChI=1S/C17H17N3O2.ClH/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H |
Inchi Key | RURAZZMDMNRXMI-UHFFFAOYSA-N |
SMILES | Cl.CN(C)CC(=O)NC1=CC2=C(NC(=O)C3=CC=CC=C23)C=C1 |
Size | 1 mg |
Supplier Page | http://www.adipogen.com/ag-cr1-0100/pj-34.html |