AMI-1
Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8 µM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0 µM).
| Catalog Number | AG-CR1-0038-M005 |
| Alternative Name(s) | Arginine N-methyltransferase inhibitor-1 |
| Research Area | Biochemicals |
| Molecular Formula | C21H12N2O9S2Na4 |
| CAS# | 20324-87-2 | 134-47-4 (free base) |
| Purity | >99% |
| Inchi | InChI=1S/C21H16N2O9S2.4Na/c24-19-9-15(33(27,28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30,31)32;;;;/h1-10,24-25H,(H2,22,23,26)(H,27,28,29)(H,30,31,32);;;;/q;4*+1/p-4 |
| Inchi Key | OEJIOAHFKHHDAW-UHFFFAOYSA-J |
| SMILES | [Na+].[Na+].[O-]C1=CC(=CC2=C1C=CC(NC(=O)NC1=CC3=C(C=C1)C([O-])=CC(=C3)S(=O)(=O)O[Na])=C2)S(=O)(=O)O[Na] |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0038/ami-1.html |