Nocodazole
Microtubule inhibitor. Antitumor compound. Mitosis inhibitor. Arrests the cell cycle at G2/M phase. Promotes tubulin depolymerization. Induces fragmentation of the Golgi complex. Inhibits the T cell antigen receptor. Stimulates the intrinsic GTPase activity of tubulin. Activates the JNK/SAPK signaling pathway. Apoptosis inducer. Autophagy inhibition through prevention of autophagosome-lysosome fusion.
| Catalog Number | AG-CR1-0019-M010 |
| Alternative Name(s) | Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate |
| Research Area | Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death |
| Molecular Formula | C14H11N3O3S |
| CAS# | 31430-18-9 |
| Purity | >98% |
| Inchi | InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19) |
| Inchi Key | KYRVNWMVYQXFEU-UHFFFAOYSA-N |
| SMILES | COC(=O)NC1=NC2=CC=C(C=C2N1)C(=O)C1=CC=CS1 |
| Size | 10 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0019/nocodazole.html |